Which statement best describes myasthenia gravis?

Which statement best describes myasthenia gravis?

• A. It is an autoimmune condition with ptosis and diplopia that worsens by end of day; prism can help.
• B. It is a bacterial infection causing droopy eyelid
• C. It is a congenital vascular disease
• D. It is a reversible corneal disease

Answer: (A)

Myasthenia gravis is an autoimmune disorder of the neuromuscular junction that causes fatigable weakness, which worsens with activity and improves with rest. In the eyes this commonly shows up as ptosis and diplopia that fluctuate and become more pronounced toward the end of the day as the extraocular muscles fatigue. The statement captures both the autoimmune basis and the characteristic fatigability pattern, and it notes that prisms can help manage the diplopia by compensating for the variable misalignment. The other descriptions don’t fit MG: a bacterial infection wouldn’t produce fatigable weakness or fluctuating lid droop; a congenital vascular disease isn’t this condition; and a reversible corneal disease affects the cornea rather than causing fatigable ptosis and diplopia.

Myasthenia gravis is an autoimmune disorder of the neuromuscular junction that causes fatigable weakness, which worsens with activity and improves with rest. In the eyes this commonly shows up as ptosis and diplopia that fluctuate and become more pronounced toward the end of the day as the extraocular muscles fatigue. The statement captures both the autoimmune basis and the characteristic fatigability pattern, and it notes that prisms can help manage the diplopia by compensating for the variable misalignment. The other descriptions don’t fit MG: a bacterial infection wouldn’t produce fatigable weakness or fluctuating lid droop; a congenital vascular disease isn’t this condition; and a reversible corneal disease affects the cornea rather than causing fatigable ptosis and diplopia.