Scleritis treatment includes which NSAID dosing?

Scleritis treatment includes which NSAID dosing?

• A. Naproxen Sodium 500 mg bid for 1-2 weeks
• B. Ibuprofen 400 mg tid for 1-2 weeks
• C. Diclofenac 50 mg qid for 2 weeks
• D. No NSAIDs are used

Answer: (A)

Systemic NSAIDs help control inflammation in non-necrotizing scleritis, so choosing a regimen that provides effective anti-inflammatory coverage with convenient dosing is key. Naproxen sodium 500 mg twice daily balances good anti-inflammatory effect with a longer half-life, allowing twice-daily dosing and typically sufficient short-term treatment for about 1–2 weeks. This makes it preferable to regimens that require more frequent dosing, such as ibuprofen 400 mg three times daily or diclofenac 50 mg four times daily, which can be harder for patients to adhere to. Not using NSAIDs isn’t appropriate for many scleritis cases treated at this level, where systemic anti-inflammatory therapy is standard.

Systemic NSAIDs help control inflammation in non-necrotizing scleritis, so choosing a regimen that provides effective anti-inflammatory coverage with convenient dosing is key. Naproxen sodium 500 mg twice daily balances good anti-inflammatory effect with a longer half-life, allowing twice-daily dosing and typically sufficient short-term treatment for about 1–2 weeks. This makes it preferable to regimens that require more frequent dosing, such as ibuprofen 400 mg three times daily or diclofenac 50 mg four times daily, which can be harder for patients to adhere to. Not using NSAIDs isn’t appropriate for many scleritis cases treated at this level, where systemic anti-inflammatory therapy is standard.