For GPC management, which is the recommended approach?

For GPC management, which is the recommended approach?

• A. Discontinue contact lens wear for 2-3 weeks and refit in daily replacement lenses
• B. Continue wearing CLs with better hygiene
• C. Switch to rigid gas-permeable lenses
• D. Stop using eye drops entirely

Answer: (A)

Giant papillary conjunctivitis from contact lens wear is driven by ongoing mechanical irritation and lens deposits. The most effective management is to stop wearing contact lenses for about two to three weeks to let the inflammation subside, then refit with daily replacement lenses to minimize deposits and lid-edge irritation. Daily disposables reduce bioburden and the mechanical forces that fuel GPC, lowering recurrence risk. Keeping lenses with improved hygiene helps, but it does not eliminate ongoing exposure that keeps the reaction active. Switching to rigid gas-permeable lenses changes the lens material and surface experience but doesn’t address the persistent inflammatory stimulus if lenses are still worn. Stopping eye drops entirely isn’t appropriate, since anti-inflammatory therapy may be needed if symptoms persist.

Giant papillary conjunctivitis from contact lens wear is driven by ongoing mechanical irritation and lens deposits. The most effective management is to stop wearing contact lenses for about two to three weeks to let the inflammation subside, then refit with daily replacement lenses to minimize deposits and lid-edge irritation. Daily disposables reduce bioburden and the mechanical forces that fuel GPC, lowering recurrence risk. Keeping lenses with improved hygiene helps, but it does not eliminate ongoing exposure that keeps the reaction active. Switching to rigid gas-permeable lenses changes the lens material and surface experience but doesn’t address the persistent inflammatory stimulus if lenses are still worn. Stopping eye drops entirely isn’t appropriate, since anti-inflammatory therapy may be needed if symptoms persist.